IGF-1 LR3 1mg

$90.00

IGF-1 LR3 is a research peptide analog of human insulin-like growth factor 1 (IGF-1) containing a 13–amino acid N-terminal extension that enhances stability and receptor binding. It interacts with the IGF-1 receptor to activate PI3K/Akt and MAPK/ERK pathways involved in cellular growth, differentiation, and metabolic regulation. IGF-1 LR3 is used in experimental models to study peptide-mediated anabolic signaling, receptor kinetics, and tissue remodeling mechanisms.

For research use only. Not for human consumption.

References:
Yakar S et al., Endocr Rev, 2001 22(6):803–817
Bach LA et al., Mol Cell Endocrinol, 2018 473:1–9
Humbel RE et al., Eur J Biochem, 1990 190(3):445–462

Category:

IGF1-LR3 (insulin-like growth factor-1 long arginine-3) is a synthetic analog of insulin-like growth factor-1 engineered for use in laboratory research. Structural modifications include N-terminal amino acid extension and substitution of glutamic acid with arginine at position three, resulting in reduced affinity for IGF-binding proteins. These modifications extend molecular persistence in experimental systems, enabling prolonged interaction with IGF-associated receptors in controlled in-vitro and in-vivo animal models.

Preclinical research utilizes IGF1-LR3 as a tool compound to investigate growth factor–mediated signaling, cellular proliferation pathways, differentiation programs, and metabolic signaling cascades. All discussion herein is limited to experimental research contexts and does not imply applied, therapeutic, or physiological use.

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